Publikationen IZKS

Originalarbeiten (Zeitschriften) im Jahr 2024

  1. Gehring S, Kowalzik F, Okasha O, Engelmann T, Schreiner S, Jensen C, Mähringer-Kunz A, Hartig-Merkel W, Mai Phuong Tran T, Oostvogels C, Verstraeten T. A prospective cohort study of SARS-CoV-2 infection-induced seroconversion and disease incidence in German healthcare workers before and during the rollout of COVID-19 vaccines. PLoS One 2024; 19: e0294025
  2. Schippers P, Gercek E, Schneidmüller D, Strohm PC, Ruckes C, Wegner E, Baranowksi A, Dietz SO. Proximal humeral fractures in children - controversies in decision making. Eur J Trauma Emerg Surg 2024; 50: 1813-1837
  3. Meyer S, Bay J, Franz AR, Erhardt H, Klein L, Petzinger J, Binder C, Kirschenhofer S, Stein A, Hüning B, Heep A, Cloppenburg E, Muyimbwa J, Ott T, Sandkötter J, Teig N, Wiegand S, Schroth M, Kick A, Wurm D, Gebauer C, Linnemann K, Kittel J, Wieg C, Kiechl-Kohlendorfer U, Schmidt S, Böttger R, Thomas W, Brevis Nunez F, Stockmann A, Kriebel T, Müller A, Klotz D, Morhart P, Nohr D, Biesalski HK, Giannopoulou EZ, Hilt S, Poryo M, Wagenpfeil S, Haiden N, Ruckes C, Ehrlich A, Gortner L, NeoVitaA trial investigators. Early postnatal high-dose fat-soluble enteral vitamin A supplementation for moderate or severe bronchopulmonary dysplasia or death in extremely low birthweight infants (NeoVitaA): a multicentre, randomised, parallel-group, double-blind, placebo-controlle. Lancet Respir Med 2024; 12: 544-555. Erratum in: Lancet Respir Med 2024; 12:e42
  4. Duwe G, Boehm K, Becker G, Ruckes C, Sparwasser P, Haack M, Dotzauer R, Thomas A, Mager R, Tsaur I, Neumann CCM, Feick G, Carl G, Brandt MP, Haferkamp A, Höfner T. Individualized center-based analysis of urinary and sexual functional outcome after radical prostatectomy based on the prostate cancer outcome study: a post hoc pathway to patient outcome measurement analysis for quality improvement. World J Urol 2024; 42: 236
  5. Legenbauer T, Kirschbaum-Lesch I, Jörke C, Kölch M, Reis O, Berger C, Dück A, Schulte-Markwort M, Becker-Hebly I, Bienioschek S, Schroth J, Ruckes C, Deuster O, Holtmann M. Bright Light Therapy as Add-On to Inpatient Treatment in Youth With Moderate to Severe Depression: A Randomized Clinical Trial. JAMA Psychiatry 2024; 81: 655-662
  6. Kreis A, Gomes A, Tsiouris A, Beutel ME, Ruckes C, Dahn I, Schiller A, Loy G, Zajac H, Kosmuetzky G, Ziser P, Sträßner E, Schneider V, Wilde T, Leber M, Schäfer H, Kilian R, Zwerenz R. Development and evaluation of an internet- and mobile-based intervention for individualized return to work planning after inpatient rehabilitation - Study protocol for a randomized-controlled-trial. Internet Interv 2024; 35: 100721
  7. Boehmer AA, Rothe M, Keim C, Nussbaum E, Wiedenmann LC, Schneider KY, Spork P, Ruckes C, Dobre BC, Kaess BM, Ehrlich JR. Pulmonary vein isolation in elderly patients ≥ 75 years: a propensity-score matched analysis with focus on differences between atrial fibrillation types. Can J Cardiol 2024; 40: 1541-1550
  8. Karampinis I, Ruckes C, Doerr F, Bölükbas S, Ricciardi S, Cardillo G, Galvez C, Vidmar B, Stupnik T, Fang V, Petersen RH, Roessner ED. ERASURE: early autologous blood pleurodesis for postoperative air leaks-a randomized, controlled trial comparing prophylactic autologous blood pleurodesis versus standard watch and wait treatment for postoperative air leaks following thoracoscopic anatom. Trials 2024; 25: 20
  9. Wirth M, Ruckes C, Michel M, Schattenberg JM. Development and validation of a multivariable risk prediction model for hepatic steatosis in patients with HIV infection. AIDS 2024; 38: 447-454
  10. Singer S, Bayer O, Schranz M, Ohler A, Herold S, Popow J, Warnke N, Malm H, Deuster O, Kronfeld K, Heß G. Patient-reported outcomes in medical registries. Experiences from an application-accompanying data collection. Onkologie 2024; 30: 304-311
  11. Schultheis M, Grabbe S, Staubach P, Hennig K, Mauch M, Burckhardt M, Langer G, Heise M, Zamsheva M, Schollenberger L, Strobel A. Drivers of disease severity and burden of hidradenitis suppurativa: a cross-sectional analysis on 553 German patients. Int J Dermatol 2024; 63: 188-195
  12. Betz U, Clarius M, Krieger M, Konradi J, Kuchen R, Schollenberger L, Wiltink J, Drees P. Time-Dependent Prediction Models for Individual Prognosis of Chronic Postsurgical Pain following Knee Replacement Based on an Extensive Multivariable Data Set. J Clin Med 2024; 13: 862
  13. Abel B, Bongartz M, Rapp K, Roigk P, Peiter J, Metz B, Finger B, Büchele G, Wensing M, Roth C, Schmidberger O, König HH, Gottschalk S, Dams J, Deuster O, Immel D, Micol W, Bauer JM, Benzinger P. Multimodal home-based rehabilitation intervention after discharge from inpatient geriatric rehabilitation (GeRas): study protocol for a multicenter randomized controlled trial. BMC Geriatr 2024; 24: 69
  14. Meyer S, Hess S, Poryo M, Papan C, Simon A, Welcker S, Ehrlich A, Ruckes C. Study draft: “UVC—You Will See” study: longer vs. shorter umbilical venous catheter (UVC) dwell time (6–10 vs. 1–5 days) in very premature infants with birth weight < 1250 g and/or gestational age < 30 weeks. Wien Med Wochenschr 2024; 174: 217-224
  15. Kowalzik F, Teschner D, Mesquita M, Jensen C, Schreiner D, Kronfeld K, Tubic-Grozdanis M, Cheatham-Seitz D, Hettich F, Quintini G, Schoenborn-Kellenberger O, Codó P, von Eisenhart-Rothe P, Mann P, Oostvogels L, Gehring S. A phase 3, randomised, observer-blinded, placebo controlled-trial evaluating the safety and immunogenicity of investigational SARS-CoV-2 mRNA vaccine CVnCoV in adult healthcare workers in Mainz (Germany). Vaccine X 2024; 19: 100512
  16. Korb CA, Gerstenberger E, Lorenz K, Bell K, Beck A, Scheller Y, Beutgen VM, Wolters D, Grus FH. Correlation of Functional and Structural Outcomes with Serum Antibody Profiles in Patients with Neovascular Age-Related Macular Degeneration Treated with Ranibizumab and Healthy Subjects: A Prospective, Controlled Monocenter Trial. . Journal of Clinical Medicine 2024; 13: 7033
  17. Pers YM, Soler-Rich R, Vadalà G, Ferreira R, Duflos C, Picot MC, Herman F, Broussous S, Sánchez A, Noriega D, Ardura F, Alberca Zaballos M, García V, Gordillo Cano V, González-Vallinas M, Denaro V, Russo F, Guicheux J, Vilanova J, Orozco L, Meisel HJ, Alfonso M, Rannou F, Maugars Y, Berenbaum F, Barry FP, Tarte K, Louis-Plence P, Ferreira-Dos-Santos G, García-Sancho J, Jorgensen C, RESPINE Consortium. Allogenic bone marrow-derived mesenchymal stromal cell-based therapy for patients with chronic low back pain: a prospective, multicentre, randomised placebo controlled trial (RESPINE study). Ann Rheum Dis 2024; 83: 1572-1583
  18. Stewen K, Droste A, Ruckes C, Elger T, Theis S, Heimes AS, Schmidt MW, Schiestl LJ, Klecker PH, Almstedt K, Schmidt M, Brenner W, Hasenburg A, Schwab R. Changes in modifiable risk factors in women at increased risk for breast and ovarian cancer during the COVID-19 pandemic. Heliyon 2024; 10: e35417
  19. Boehmer AA, Rothe M, Ruckes C, Eckardt L, Kaess BM, Ehrlich JR. Catheter Ablation for Atrial Fibrillation in Elderly Patients: an Updated Meta-analysis of Comparative Studies. Can J Cardiol 2024; : Im Druck
  20. Pordzik J, Ludwig K, Seifen C, Ruckes C, Huppertz T, Bahr-Hamm K, Hackenberg B, Matthias C, Gouveris H. Real-world data on polysomnography- and patient-reported outcomes in hypoglossal nerve stimulation and auto-titrating positive airway pressure therapy for obstructive sleep apnea. Respir Med 2024; 232: 107750
  21. Boehmer AA, Schubert T, Rothe M, Keim C, Wiedenmann L, Ruckes C, von Stuelpnagel L, Theurl F, Schreinlechner M, Dobre BC, Kaess BM, Bauer A, Ehrlich JR. Angiotensin Receptor-Neprilysin Inhibitor Is Associated With Improved Cardiac Autonomic Function in Heart Failure. J Am Heart Assoc 2024; 13: e033538
  22. Boehmer AA, Kaess BM, Ruckes C, Meyer C, Metzner A, Rillig A, Eckardt L, Nattel S, Ehrlich JR. Pulmonary Vein Isolation or Pace and Ablate in Elderly Patients With Persistent Atrial Fibrillation (ABLATE Versus PACE)-Rationale, Methods, and Design. Can J Cardiol 2024; : Im Druck
  23. Haack M, Ruckes C, Dotzauer R, Thomas A, Sparwasser MP, Fischer ND, Frey LJ, Duwe G, Haferkamp A, Tsaur I, Brandt MP. Comparative Retrospective Assessment of the Effectiveness and Risk Factors of Fluoroquinolones, Cephalosporines, and Selective Antibiotic Prophylaxis for Transrectal Prostate Biopsy. Urol Int 2024; 108: 406-413
  24. Mohr M, Büttner M, Deuster O, Heckmann J, Huwer F, Krämer I, Lippold C, Siegrist B, Singer S, Veith M, Zinke A, Hardt R. E-Health-based, trans-sectoral, geriatric health service - Geriatric Network (GerNe). Sci Rep 2024; 14: 17326

Originalarbeiten (Zeitschriften) im Jahr 2023

  1. Kneist W, Ghadimi M, Runkel N, Moesta T, Coerper S, Benecke C, Kauff DW, Gretschel S, Gockel I, Jansen-Winkeln B, Lang H, Gorbulev S, Ruckes C, Kronfeld K, NEUROS Study Group. Pelvic Intraoperative Neuromonitoring Prevents Dysfunction in Patients with Rectal Cancer: Results from a Multicenter, Randomized, Controlled Clinical Trial of a NEUROmonitoring System (NEUROS). Ann Surg 2023; 277: e737-e744
  2. Kämmerer PW, Tribius S, Cohrs L, Engler G, Ettl T, Freier K, Frerich B, Ghanaati S, Gosau M, Haim D, Hartmann S, Heiland M, Herbst M, Hoefert S, Hoffmann J, Hölzle F, Howaldt HP, Kreutzer K, Leonhardt H, Lutz R, Moergel M, Modabber A, Neff A, Pietzka S, Rau A, Reichert TE, Smeets R, Sproll C, Steller D, Wiltfang J, Wolff KD, Kronfeld K, Al-Nawas B. Adjuvant Radiotherapy in Patients with Squamous Cell Carcinoma of the Oral Cavity or Oropharynx and Solitary Ipsilateral Lymph Node Metastasis (pN1)-A Prospective Multicentric Cohort Study. Cancers (Basel) 2023; 15: 1833
  3. Anic K, Flohr F, Schmidt MW, Krajnak S, Schwab R, Schmidt M, Westphalen C, Eichelsbacher C, Ruckes C, Brenner W, Hasenburg A, Battista MJ. Frailty assessment tools predict perioperative outcome in elderly patients with endometrial cancer better than age or BMI alone: a retrospective observational cohort study. J Cancer Res Clin Oncol 2023; 149: 1551-1560
  4. Fritsche T, Schnetz M, Klug A, Fischer S, Ruckes C, Hunfeld KP, Hoffmann R, Gramlich Y. Tissue sampling is non-inferior in comparison to sonication in orthopedic revision surgery. Arch Orthop Trauma Surg 2023; 143: 2901-2911
  5. Hess S, Poryo M, Böttger R, Franz A, Klotz D, Linnemann K, Ott T, Pöschl J, Schroth M, Stein A, Ralser E, Reutter H, Thome UH, Wieg C, Ehrlich A, Ruckes C, Wagenpfeil S, Zemlin M, Papan C, Simon A, Bay J, Meyer S. Umbilical venous catheter- and peripherally inserted central catheter-associated complications in preterm infants with birth weight < 1250 g : Results from a survey in Austria and Germany. Wien Med Wochenschr 2023; 173: 161-167
  6. Anic K, Varchola J, Schmidt MW, Schwab R, Linz VC, Schmidt M, Hardt R, Hartmann EK, Ruckes C, Hasenburg A, Battista MJ. Influence of interdisciplinary frailty screening on perioperative complication rates in elderly ovarian cancer patients: results of a retrospective observational study. Arch Gynecol Obstet 2023; 307: 1929-1940
  7. Steindor M, Hafkemeyer S, Ruckes C, Stehling F, Naehrlich L, Ringshausen FC. Epidemiological trends in nontuberculous mycobacterial infection among people with cystic fibrosis in Germany. Int J Infect Dis 2023; 129: 32-39
  8. Müller KW, Dreier M, Beutel ME, Ruckes C, Batra A, Mann K, Musalek M, Wölfling K. The impact of life satisfaction in the treatment of gaming disorder and other internet use disorders: Results from a randomized controlled trial. J Behav Addict 2023; 12: 159-167
  9. Gramlich Y, Schnetz M, Ruckes C, Kemmerer M, Kremer M, Hoffmann R, Klug A. The optimal diagnostic cut-off of WBC and PMN counts for joint aspiration in periprosthetic joint infection is 2479/µL and 67%, respectively: ICM criteria thresholds are too high. Arch Orthop Trauma Surg 2023; 143: 5229-5238
  10. Hess S, Poryo M, Ruckes C, Papan C, Ehrlich A, Ebrahimi-Fakhari D, Bay JS, Wagenpfeil S, Simon A, Meyer S. Assessment of an umbilical venous catheter dwell-time of 8-14 days versus 1-7 days in very low birth weight infacts (UVC - You Will See): a pilot single-center, randomized controlled trial. Early Hum Dev 2023; 179: 105752
  11. Schippers P, Drees P, Gercek E, Wunderlich F, Müller D, Ruckes C, Meyer A, Klein S, Fischer S. The Controversial Definition of Normal Toe Alignment. J Clin Med 2023; 12: 3509
  12. Boehmer AA, Rothe M, Nussbaum E, Ruckes C, Dobre BC, Kaess BM, Ehrlich JR. Cryoballoon pulmonary vein isolation for atrial fibrillation in obese patients: A non-inferiority analysis. Int J Cardiol Heart Vasc 2023; 47: 101244
  13. Ader L, Schick A, Löffler M, Löffler A, Beiner E, Eich W, Vock S, Sirazitdinov A, Malone C, Hesser J, Hopp M, Ruckes C, Flor H, Tesarz J, Reininghaus U. Refocusing of Attention on Positive Events Using Monitoring-Based Feedback and Microinterventions for Patients With Chronic Musculoskeletal Pain in the PerPAIN Randomized Controlled Trial: Protocol for a Microrandomized Trial. JMIR Res Protoc 2023; 12: e43376
  14. Duwe G, Müller L, Ruckes C, Fischer ND, Frey LJ, Börner JH, Rölz N, Haack M, Sparwasser P, Jorg T, Neumann CCM, Tsaur I, Höfner T, Haferkamp A, Hahn F, Mager R, Brandt MP. Change in Splenic Volume as a Surrogate Marker for Immunotherapy Response in Patients with Advanced Urothelial and Renal Cell Carcinoma-Evaluation of a Novel Approach of Fully Automated Artificial Intelligence Based Splenic Segmentation. Biomedicines 2023; 11: 2482
  15. Schippers P, Meurer A, Schnetz M, Ewald L, Ruckes C, Hoffmann R, Gramlich Y. A Novel Tool for Collaborative and Blinded Orthopedic Image Analysis. Life (Basel) 2023; 13: 1805
  16. Tsiouris A, Mayer A, Wiltink J, Ruckes C, Beutel ME, Zwerenz R. Recruitment of Patients With Cancer for a Clinical Trial Evaluating a Web-Based Psycho-Oncological Intervention: Secondary Analysis of a Diversified Recruitment Strategy in a Randomized Controlled Trial. JMIR Cancer 2023; 9: e42123
  17. Heise M, Staubach P, Nikolakis G, Schollenberger L, Mauch M, Burckhardt M, Zamsheva M, Strobel A, Langer G, Bechara F, Kirschner U, Hennig K, Kunte C, Goebeler M, Podda M, Grabbe S, Schultheis M. A center-based, ambulatory care concept for hidradenitis suppurativa improves patient outcomes and is also cost-effectiveness. J Dermatolog Treat 2023; 34: 2284105
  18. Schultheis M, Staubach P, Nikolakis G, Schollenberger L, Mauch M, Burckhardt M, Heise M, Zamsheva M, Strobel A, Langer G, Bechara F, Kirschner U, Hennig K, Kunte C, Goebeler M, Grabbe S. A centre-based ambulatory care concept for hidradenitis suppurativa improves disease activity, disease burden and patient satisfaction: results from the randomized controlled EsmAiL trial. Br J Dermatol 2023; 189: 170-179

Originalarbeiten (Zeitschriften) im Jahr 2022

  1. Griese M, Kappler M, Stehling F, Schulze J, Baden W, Koerner-Rettberg C, Carlens J, Prenzel F, Nährlich L, Thalmeier A, Sebah D, Kronfeld K, Rock H, Ruckes C, HCQ-study group, Wetzke M, Seidl E, Schwerk N. Randomized controlled phase 2 trial of hydroxychloroquine in childhood interstitial lung disease. Orphanet J Rare Dis 2022; 17: 289
  2. Schultheis M, Staubach P, Nikolakis G, Grabbe S, Ruckes C, von Stebut E, Kirschner U, Matusiak Ł, Szepietowski JC. LAight® Therapy Significantly Enhances Treatment Efficacy of 16 Weeks of Topical Clindamycin Solution in Hurley I and II Hidradenitis Suppurativa: Results from Period A of RELIEVE, a Multicenter Randomized, Controlled Trial. Dermatology 2022; 238: 476-486
  3. Pitton MB, Weinmann A, Kloeckner R, Mittler J, Ruckes C, Düber C, Otto G. Transjugular Portosystemic Stent Shunt: Impact of Right Atrial Pressure on Portal Venous Hemodynamics Within the First Week. Cardiovasc Intervent Radiol 2022; 45: 102-111
  4. Brandt MP, Ruf C, Dieckmann KP, Syring I, Ruckes C, Nestler T, Schmelz HU, Dotzauer R, Hiester A, Albers P, Nettersheim D, Bolenz C, Loosen SH, Heidenreich A, Pfister D, Haferkamp A, Zengerling F, Pfaffenholz P, GESRU Academics Testis, Penile Cancer Group. Clinical characteristics, treatment patterns and relapse in patients with clinical stage IS testicular cancer. World J Urol 2022; 40: 327-334
  5. Witzel S, Maier A, Steinbach R, Grosskreutz J, Koch JC, Sarikidi A, Petri S, Günther R, Wolf J, Hermann A, Prudlo J, Cordts I, Lingor P, Löscher WN, Kohl Z, Hagenacker T, Ruckes C, Koch B, Spittel S, Günther K, Michels S, Dorst J, Meyer T, Ludolph AC, German Motor Neuron Disease Network (MND-NET). Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis. JAMA Neurol 2022; 79: 121-130
  6. Gramlich Y, Hofmann L, Kress S, Ruckes C, Kemmerer M, Klug A, Hoffmann R, Kremer M. Critically high metal ion levels found in metal-on-metal modular hinged knee arthroplasty : a comparison of two different systems. Bone Joint J 2022; 104-B: 376-385
  7. Tsaur I, van den Bergh RCN, Soeterik T, Thomas A, Brandt MP, Zattoni F, Dal Moro F, Morlacco A, Collavino J, Ploussard G, Surcel C, Mirvald C, Carmona O, Rosenzweig B, Ruckes C, Heisinger T, Heidegger I, Gandaglia G, Dotzauer R, European Association of Urology Young Academic Urologists Prostate Cancer Working Party. Predictors of Unfavorable Pathology in Patients with Incidental (pT1a-T1b) Prostate Cancer. Eur Urol Focus 2022; 8: 1599-1606
  8. Hess G, Hüttmann A, Witzens-Harig M, Dreyling MH, Keller U, Marks R, Ernst T, Pott C, Viardot A, Frontzek F, Trautmann M, Ruckes C, Deuster O, Rosenwald A, Theobald M, Lenz G. A phase II trial to evaluate the combination of pixantrone and obinutuzumab for patients with relapsed aggressive lymphoma: Final results of the prospective, multicentre GOAL trial. Br J Haematol 2022; 198: 482-491
  9. Schultheis M, Staubach P, Grabbe S, Ruckes C, von Stebut E, Kirschner U, Matusiak Ł, Szepietowski JC, Nikolakis G. LAight® Therapy Is an Effective Treatment Option to Maintain Long-Term Remission of Hurley I and II Hidradenitis Suppurativa: Results from Period B of RELIEVE, a Multicenter Randomized, Controlled Trial. Dermatology 2022; 238: 1092-1103
  10. Bell K, Korb C, Butsch C, Giers BC, Beck A, Strzalkowska A, Ruckes C, Klingberg U, Pfeiffer N, Lorenz K. A Randomized, Double-Masked, Active-Controlled, Crossover Phase III Equivalence Study of Generic Dorzolamide 2% versus Innovator Trusopt® Eye Drop Solution in Subjects with Open-Angle Glaucoma or Ocular Hypertension. J Ophthalmol 2022; 2022: 5249922
  11. Hagenbusch P, Faul P, Ruckes C, Störmann P, Marzi I, Hoffmann R, Schweigkofler U, Gramlich Y. The predictive value of serum lactate to forecast injury severity in trauma-patients increases taking age into account. Eur J Trauma Emerg Surg 2022; : Im Druck
  12. Hennemann S, Böhme K, Kleinstäuber M, Ruckes C, Baumeister H, Ebert DD, Küchler AM, Witthöft M. Is Therapist Support Needed? Comparing Therapist- and Self-Guided Internet-Based CBT for Somatic Symptom Distress (iSOMA) in Emerging Adults. Behav Ther 2022; 53: 1205-1218
  13. Anic K, Schmidt MW, Furtado L, Weidenbach L, Battista MJ, Schmidt M, Schwab R, Brenner W, Ruckes C, Lotz J, Lackner KJ, Hasenburg A, Hasenburg A. Intermittent Fasting-Short- and Long-Term Quality of Life, Fatigue, and Safety in Healthy Volunteers: A Prospective, Clinical Trial. Nutrients 2022; 14: 4216
  14. Beiner E, Baumeister D, Buhai D, Löffler M, Löffler A, Schick A, Ader L, Eich W, Sirazitdinov A, Malone C, Hopp M, Ruckes C, Hesser J, Reininghaus U, Flor H, Tesarz J, PerPain consortium. The PerPAIN trial: a pilot randomized controlled trial of personalized treatment allocation for chronic musculoskeletal pain-a protocol. Pilot Feasibility Stud 2022; 8: 251
  15. Betz U, Langanki L, Heid F, Schollenberger L, Kronfeld K, Büttner M, Büchler B, Eckhard L, Klonschinski T, Drees P. Feasibility of a Complex Optimized Process for the Treatment of Patients Receiving Hip and Knee Endoprostheses in Most Different Settings in Germany—Results from the PROMISE Trial. Processes 2022; 10: 824

Originalarbeiten (Zeitschriften) im Jahr 2021

  1. NeoVitaA Study Group. COVID-19-induced collateral damage. Wien Med Wochenschr 2021; 171: 7-8
  2. Betz U, Langanki L, Heid F, Spielberger J, Schollenberger L, Kronfeld K, Büttner M, Büchler B, Goldhofer M, Eckhard L, Drees P, PROMISE GROUP. The PROMISE study protocol: a multicenter prospective study of process optimization with interdisciplinary and cross-sectoral care for German patients receiving hip and knee endoprostheses. Acta Orthop 2021; 92: 156-162
  3. Griese M, Stehling F, Schwerk N, Rosewich M, Jerkic PS, Rock H, Ruckes C, Kronfeld K, Sebah D, Wetzke M, Seidl E. Hypersensitivity pneumonitis: Lessons from a randomized controlled trial in children. Pediatr Pulmonol 2021; 56: 2627-2633
  4. Dotzauer R, La Torre A, Thomas A, Brandt MP, Böhm K, Mager R, Borgmann H, Jäger W, Kurosch M, Höfner T, Ruckes C, Haferkamp A, Tsaur I. Robot-assisted simple prostatectomy versus open simple prostatectomy: a single-center comparison. World J Urol 2021; 39: 149-156
  5. Huppertz T, Horstmann V, Scharnow C, Ruckes C, Bahr K, Matthias C, Gouveris H. OSA in patients with head and neck cancer is associated with cancer size and oncologic outcome. Eur Arch Otorhinolaryngol 2021; 278: 2485-2491
  6. Krajnak S, Decker T, Schollenberger L, Rosé C, Ruckes C, Fehm T, Thomssen C, Harbeck N, Schmidt M. Phase II study of metronomic treatment with daily oral vinorelbine as first-line chemotherapy in patients with advanced/metastatic HR+/HER2- breast cancer resistant to endocrine therapy: VinoMetro-AGO-B-046. J Cancer Res Clin Oncol 2021; 147: 3391-3400
  7. Tsiouris A, Mayer A, Nölke C, Ruckes C, Labitzke N, Wiltink J, Beutel ME, Zwerenz R. An emotion-based online intervention for reducing anxiety and depression in cancer patients: Study protocol for a randomized controlled trial. Internet Interv 2021; 25: 100410
  8. Aggensteiner PM, Albrecht B, Strehl U, Wörz S, Ruckes C, Freitag CM, Rothenberger A, Gevensleben H, Millenet S, Hohmann S, Banaschewski T, Legenbauer T, Holtmann M, Brandeis D. Can neurophysiological markers of anticipation and attention predict ADHD severity and neurofeedback outcomes?. Biol Psychol 2021; 165: 108169
  9. Witzens-Harig M, Viardot A, Keller U, Wosniok J, Deuster O, Klemmer J, Geueke AM, Meißner J, Ho AD, Atta J, Marks R, La Rosée P, Buske C, Dreyling MH, Hess G. The mTOR Inhibitor Temsirolimus Added to Rituximab Combined With Dexamethasone, Cytarabine, and Cisplatinum (R-DHAP) for the Treatment of Patients With Relapsed or Refractory DLBCL - Results From the Phase-II STORM Trial. Hemasphere 2021; 5: e636

Originalarbeiten (Zeitschriften) im Jahr 2020

  1. Cunningham S, Graham C, MacLean M, Aurora P, Ashworth M, Barbato A, Calder A, Carlens J, Clement A, Hengst M, Kammer B, Kiper N, Krenke K, Kronfeld K, Lange J, Ley-Zaporozhan J, Nicholson AG, Reu S, Wesselak T, Wetzke M, Bush A, Schwerk N, Griese M, ChILDEU study group. ChILDEU study group. One-year outcomes in a multicentre cohort study of incident rare diffuse parenchymal lung disease in children (ChILD. Thorax 2020; 75: 172-175
  2. Griese M, Köhler M, Witt S, Sebah D, Kappler M, Wetzke M, Schwerk N, Emiralioglu N, Kiper N, Kronfeld K, Ruckes C, Rock H, Anthony G, Seidl E. Prospective evaluation of hydroxychloroquine in pediatric interstitial lung diseases: Study protocol for an investigator-initiated, randomized controlled, parallel-group clinical trial. Trials 2020; 21: 307
  3. Fousse M, Grün D, Helwig SA, Walter S, Bekhit A, Wagenpfeil S, Lesmeister M, Kettner M, Roumia S, Mühl-Benninghaus R, Simgen A, Yilmaz U, Ruckes C, Kronfeld K, Bachhuber M, Grunwald IQ, Bertsch T, Reith W, Fassbender K. Effects of a Feedback-Demanding Stroke Clock on Acute Stroke Management: A Randomized Study. Stroke 2020; 51: 2895-2900
  4. Hofmann A, Gorbulev S, Guehring T, Schulz AP, Schupfner R, Raschke M, Huber-Wagner S, Rommens PM, CERTiFy Study Group. Autologous Iliac Bone Graft Compared with Biphasic Hydroxyapatite and Calcium Sulfate Cement for the Treatment of Bone Defects in Tibial Plateau Fractures: A Prospective, Randomized, Open-Label, Multicenter Study. J Bone Joint Surg Am 2020; 102: 179-193
  5. Hess G, Wagner K, Keller U, La Rosee P, Atta J, Hübel K, Lerchenmueller C, Schoendube D, Witzens-Harig M, Ruckes C, Medler C, van Oordt C, Klapper W, Theobald M, Dreyling M. Final Results of a Phase I/II Trial of the Combination Bendamustine and Rituximab With Temsirolimus (BeRT) in Relapsed Mantle Cell Lymphoma and Follicular Lymphoma. Hemasphere 2020; 4: e398
  6. Schulz M, Griese-Mammen N, Schumacher PM, Anker SD, Koehler F, Ruckes C, Rettig-Ewen V, Wachter R, Trenk D, Böhm M, Laufs U. The impact of pharmacist/physician care on quality of life in elderly heart failure patients: results of the PHARM-CHF randomized controlled trial. ESC Heart Fail 2020; 7: 3310-3319
  7. Prinz N, Wosniok J, Staab D, Ballmann M, Dopfer C, Regenfuß N, Rosenecker J, Schramm D, Holl W R, Nährlich L. Glucose Tolerance in Patients with Cystic Fibrosis - Results from the German Cystic Fibrosis Registry. Klin Padiatr 2020; 232: 210-216
  8. Schnorbus B, Daiber A, Jurk K, Warnke S, Koenig J, Lackner KJ, Münzel T, Gori T. Effects of clopidogrel vs. prasugrel vs. ticagrelor on endothelial function, inflammatory parameters, and platelet function in patients with acute coronary syndrome undergoing coronary artery stenting: a randomized, blinded, parallel study. Eur Heart J 2020; 41: 3144-3152

Originalarbeiten (Zeitschriften) im Jahr 2019

  1. Klimas , Gorfinkel , Giacomuzzi , Ruckes , Socias , Fairbairn , Wood . Slow release oral morphine versus methadone for the treatment of opioid use disorder. BMJ OPEN 2019; 9: e025799
  2. Wölfling K, Müller KW, Dreier M, Ruckes C, Deuster O, Batra A, Mann K, Musalek M, Schuster A, Lemenager T, Hanke S, Beutel ME. Efficacy of Short-term Treatment of Internet and Computer Game Addiction: A Randomized Clinical Trial. JAMA Psychiatry 2019; 76: 1018-1025
  3. Schulz M, Griese-Mammen N, Anker SD, Koehler F, Ihle P, Ruckes C, Schumacher PM, Trenk D, Böhm M, Laufs U. Pharmacy-based interdisciplinary Intervention for patients with chronic heart failure: results of the PHARM-CHF randomized controlled trial. Eur J Heart Fail 2019; 21: 1012-1021
  4. Moehler M, Maderer A, Ehrlich A, Foerster F, Schad A, Nickolay T, Ruckes C, Weinmann A, Sivanathan V, Marquardt JU, Galle PR, Woerns M, Thomaidis T. Safety and efficacy of afatinib as add-on to Standard therapy of gemcitabine/Cisplatin in chemotherpay-naive patients with advanced biliary tract Cancer: open-label, phase I Trial with an extensive biomarker program. BMC Cancer 2019; 19: 55
  5. Aggensteiner PM, Brandels D, Millenet S, Hohmann S, Ruckes C, Beuth S, Albrecht B, Schmitt G, Schermuly S, Wörz S, Gevensleben H, Freitag CM, Banaschewski T, Rothenberger A, Strehl U, Holtmann M. Slow cortical potentials neurofeedback in Children with ADHD: comorbidity, self-regulation and clinical Outcomes 6 months after Treatment in a multicenter randomized controlled trial. Eur Child Adolesc Psych 2019; 28: 1087-1095
  6. Huber Y, Boyle M, Hallsworth K, Tiniakos D, Straub BK, Labenz C, Ruckes C, Galle PR, Romero-Gómez M, Anstee QM, Schattenberg JM, EPoS Consortium Investigators . Health-related Quality of Life in Non-alcoholic Fatty Liver Disease Associates With Hepatic Inflammation. Clin Gastroenterol Hepatol 2019; 17: 2085-2092
  7. Huber Y, Pfirrmann D, Gebhardt I, Labenz C, Gehrke N, Straub BK, Ruckes C, Bantel K, Belda E, Clément K, Leeming DJ, Karsdal MA, Galle PR, Simon P, Schattenberg JM. Improvement of non-invasive markers of NAFLD from an individualised, web-based exercise program. Aliment Pharmacol Ther 2019; 50: 930-939
  8. Helwig SA, Ragoschke-Schumm A, Schwindling L, Kettner M, Roumia S, Kulikovski J, Keller I, Manitz M, Martens D, Grün D, Walter S, Lesmeister M, Ewen K, Brand J, Fousse M, Kauffmann J, Zimmer VC, Mathur S, Bertsch T, Guldner J, Magull-Seltenreich A, Binder A, Spüntrup E, Chatzikonstantinou A, Adam O, Kronfeld K, Liu Y, Ruckes C, Schumacher H, Grunwald IQ, Yilmaz U, Schlechtriemen T, Reith W, Fassbender K. Prehospital Stroke Management Optimized by Use of Clinical Scoring vs Mobile Stroke Unit for Triage of Patients With Stroke: A Randomized Clinical Trial. JAMA Neurol 2019; 76: 1484-1492

Originalarbeiten (Zeitschriften) im Jahr 2018

  1. Holtmann M, Mokros L, Kirschbaum-Lesch I, Kölch M, Plener PL, Ruckes C, Schulte-Markwort M, Legenbauer T. Adolescent depression: Study protocol for a randomized, controlled, double-blind multicenter parallel group trial of Bright Light Therapy in a naturalistic inpatient Setting (DeLight). Trials 2018; 19: 568
  2. Labenz C, Huber Y, Kalliga E, Nagel M, Ruckes C, Straub BK, Galle PR, Wörns MA, Anstee QM, Schuppan D, Schattenberg JM. Predictors of advanced fibrosis in non-cirrhotic non-alcoholic fatty liver disease in Germany. Aliment Pharmacol Ther 2018; 48: 1109-1116
  3. Mulfinger N, Müller S, Böge I, Sakar V, Corrigan PW, Evans-Lacko S, Nehf L, Djamali J, Samarelli A, Kempter M, Ruckes C, Libal G, Oexle N, Noterdaeme M, Rüsch N. Honest, Open, Proud for adolescents with mental illness: pilot randomized controlled trial. J Child Psychol Psychiatry 2018; 59: 684-691
  4. Ballmann M, Hubert D, Assael BM, Staab D, Hebestreit A, Naehrlich L, Nickolay T, Prinz N, Holl RW, CFRD Study Group . Repaglinide versus Insulin for newly diagnosed Diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised Trial. Lancet Diabetes Endocrinol 2018; 6: 114-121

Originalarbeiten (Zeitschriften) im Jahr 2017

  1. Wiltink J, Ruckes C, Hoyer J, Leichsenring F, Joraschky P, Leweke F, Pöhlmann K, Beutel ME. Transfer of manualized Short Term Psychodynamic Psychotherapy (STPP) for social anxiety disorder into clinical practice: results from a cluster-randomised controlled trial . BMC Psychiatry 2017; 17: 92
  2. Herzog DP, Wagner S, Ruckes C, Tadic A, Roll SC, Härtner M, Lieb K. Guideline adherence of antidepressant treatment in outpatients with major depressive disorder: a naturalistic study. Eur Arch Psychiatry Clin Neurosci 2017; 267: 711-721
  3. Franke AG, Gränsmark P, Agricola P, Schühle K, Rommel T, Sebastian A, Balló HE, Gorbulev S, Gerdes C, Frank B, Ruckes C, Tüscher O, Lieb K. Methylphenidate, modafinil, and caffeine for cognitive enhancement in chess: A double-blind, randomised controlled trial. Eur Neuropsychopharmacol 2017; 27: 248-260
  4. Lorenz K, Wasielica-Poslednik J, Bell K, Renieri G, Keicher A, Ruckes C, Pfeiffer N, Thieme H. Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. PLoS One 2017; 12: e0171636
  5. Strehl U, Aggensteiner P, Wachtlin D, Brandeis D, Albrecht B, Arana M, Bach C, Banaschewski T, Flaig-Röhr A, Freitag CM, Fuchsenberger Y, Gest S, Gevensleben H, Herde L, Legenbauer T, Marx AM, Millenet S, Pniewski B, Rothenberger A, Ruckes C, Wörz S, Holtmann M. Neurofeedback of Slow Cortical Potentials in Children with Attention-Deficit/Hyperactivity Disorder: A Multicenter Randomized Trial Controlling for Unspecific Effects. Front Hum Neurosci 2017; 11: 135
  6. Jaithe LES, Helwig SA, Jaqne A, Ragoschke-Schumm A, Sarr C, Walter S, Lesmeister M, Manitz M, Blaß D, Weis S, Schlund V, Bah N, Kauffmann J, Fousse M, Kangankan S, Ramos Cabrera A, Kronfeld K, Ruckes C, Liu Y, Nyan O, Fassbender K. Standard operating procedures improve acute neurologic care in a sub-Saharan African Setting. Neurology 2017; 89: 144-152
  7. Kahaly GJ, Riedl M, König J, Diana T, Schomburg L. Double-Blind, Placebo-Controlled, Randomized Trial of Selenium in Graves Hyperthyroidism. J Clin Endocrinol Metab 2017; 102: 4333-4341
  8. Meyer , Gortner L, NeoVitaA Trial investigators . Up-date on the NeoVitaA Trial: Obstacles, challenges, perspectives, and local experiences. Wien Med Wochenschr 2017; 167: 264-270
  9. Otto G, Heise M, Thies J, Pitton M, Schneider J, Kaiser G, Neuhaus P, Kollmar O, Barthels M, Geks J, Bechstein WO, Hellinger A, Klempnauer J, Padberg W, Frühauf N, Ebbing A, Mauer D, Schneider A, Kwiecien R, Kronfeld K. Liver Preservation by Aortic Perfusion Alone Compared With Preservation by Aortic Perfusion and Additional Arterial Ex Situ Back-Table Perfusion With Histidine-Tryptophan-Ketoglutarate Solution: A Prospective, Randomized, Controlled, Multicenter Study. Transplant Direct 2017; 3: e183

Originalarbeiten (Zeitschriften) im Jahr 2016

  1. Wiltink J, Hoyer J, Beutel ME, Ruckes C, Herpertz S, Joraschky P, Koranyi S, Michal M, Nolting B, Pöhlmann K, Salzer S, Strauss B, Leibing E, Leichsenring F. Do patient characteristics predict outcome of psychodynamic psychotherapy for social anxiety disorder?. PLoS ONE 2016; 11: e0147165
  2. Ferner M, Wachtlin D, Konrad T, Deuster O, Meinertz T, von Bardeleben S, Münzel T, Seibert-Grafe M, Breithardt G, Rostock T. Rationale and design of the RE-LATED AF-AFNET 7 trial: REsolution of Left atrial-Appendage Thrombus-Effects of Dabigatran in patients with Atrial Fibrillation. Clin Res Cardiol 2016; 105: 29-36
  3. Tadić A, Wachtlin D, Berger M, Braus DF, van Calker D, Dahmen N, Dreimüller N, Engel A, Gorbulev S, Helmreich I, Kaiser AK, Kronfeld K, Schlicht KF, Tüscher O, Wagner S, Hiemke C, Lieb K. Randomized controlled study of early medication change for non-improvers to antidepressant therapy in major depression - the EMC trial. Eur Neuropsychopharmacol 2016; 26: 705-16
  4. Kauff DW, Kronfeld K, Gorbulev S, Wachtlin D, Lang H, Kneist W. Continuous intraoperative monitoring of pelvic autonomic nerves during TME to prevent urogenital and anorectal dysfunction in rectal cancer patients (NEUROS): a randomized controlled trial. BMC Cancer 2016; 16: 323
  5. Riedl M, Kuhn A, Krämer I, Kolbe E, Kahaly GJ. Prospective, systematically recorded mycophenolate safety data in Graves' orbitopathy. J Endocrinol Invest 2016; 39: 687-94
  6. Moehler M, Gepfner-Tuma I, Maderer A, Thuss-Patience PC, Ruessel J, Hegewisch-Becker S, Wilke H, Al-Batran SE, Rafiyan MR, Weißinger F, Schmoll HJ, Kullmann F, von Weikersthal LF, Siveke JT, Weusmann J, Kanzler S, Schimanski CC, Otte M, Schollenberger L, Koenig J, Galle PR. Sunitinib added to FOLFIRI versus FOLFIRI in patients with chemorefractory advanced adenocarcinoma of the stomach or lower esophagus: a randomized, placebo-controlled phase II AIO trial with serum biomarker program. BMC Cancer 2016; 16: 699
  7. Zahn D, Herpertz S, Albus C, Hermanns N, Hiemke C, Hiller W, Kronfeld K, Kruse J, Kulzer B, Müller MJ, Ruckes C, Petrak F. hs-CRP Predicts Improvement in Depression in Patients With Type 1 Diabetes and Major Depression Undergoing Depression Treatment: Results From the Diabetes and Depression (DAD) Study. Diabetes Care 2016; 39: 171-173

Originalarbeiten (Zeitschriften) im Jahr 2015

  1. Pitton MB, Kloeckner R, Ruckes C, Wirth GM, Eichhorn W, Wörns MA, Weinmann A, Schreckenberger M, Galle PR, Otto G, Dueber C. Randomized comparison of selective internal radiotherapy (SIRT) versus drug-eluting bead transarterial chemoembolization (DEB-TACE) for the treatment of hepatocellular carcinoma. Cardiovasc Intervent Radiol 2015; 38: 352-60
  2. Hess G, Keller U, Scholz CW, Witzens-Harig M, Atta J, Buske C, Kirschey S, Ruckes C, Medler C, van Oordt C, Klapper W, Theobald M, Dreyling M. Safety and efficacy of temsirolimus in combination with bendamustine and rituximab in relapsed mantle cell and follicular lymphoma. Leukemia 2015; 29: 1695-701
  3. Werhahn KJ, Trinka E, Dobesberger J, Unterberger I, Baum P, Deckert-Schmitz M, Kniess T, Schmitz B, Bernedo V, Ruckes C, Ehrlich A, Krämer G. A randomized, double-blind comparison of antiepileptic drug treatment in the elderly with new-onset focal epilepsy. Epilepsia 2015; 56: 450-9
  4. Petrak F, Herpertz S, Albus C, Hermanns N, Hiemke C, Hiller W, Kronfeld K, Kruse J, Kulzer B, Ruckes C, Zahn D, Müller MJ. Cognitive behavioral therapy versus sertraline in patients with depression and poorly controlled diabetes: the diabetes and depression (DAD) study: a randomized controlled multicenter trial. Diabetes Care 2015; 38: 767-75
  5. Kloeckner R, Weinmann A, Prinz F, Pinto dos Santos D, Ruckes C, Dueber C, Pitton MB. Conventional transarterial chemoembolization versus drug-eluting bead transarterial chemoembolization for the treatment of hepatocellular carcinoma. BMC Cancer 2015; 15: 465
  6. Adrian M, Wachtlin D, Kronfeld K, Sommerfeldt D, Wessel LM. A comparison of intervention and conservative treatment for angulated fractures of the distal forearm in children (AFIC): study protocol for a randomized controlled trial. Trials 2015; 16: 437
  7. Sprinzl MF, Grambihler A, Kittner JM, Wachtlin D, Ruckes C, Schattenberg J, Ehrlich A, Alshuth U, Wörns M, Schuchmann M, Galle PR. Prospective randomized open-label trial protocol investigating the addition of pegylated interferon-alpha to an ongoing nucleos(t)ide treatment regimen of HBeAg negative chronic hepatitis B patients (PADD-ON). J Clin Trials 2015; 5: 226
  8. Riedl M, Kolbe E, Kampmann E, Krämer I, Kahaly GJ. Prospectively recorded and MedDRA-coded safety data of intravenous methylprednisolone therapy in Graves' orbitopathy. J Endocrinol Invest 2015; 38: 177-82

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